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Scutellaria lateriflora L. (Skullcap)

SCIENTIFIC NAME

Scutellaria lateriflora L.

COMMON NAME

Skullcap
Mad dog skullcap
Blue skullcap
Side flowering skullcap
Huang Qin (TCM)

PARTS USED

Aerial

CONSTITUENTS

Flavinoids (baicalein, baicalin, scutellarein, and wogonin)
Iridoids (including catalpol)
Volotile oil
Tanins

ACTIONS

Nervine tonic
Antispasmodic
Hypotensive
Analgesic (anodyne)
Antispasmodic
Sedative
Soporific (hypnotic)

ENERGETICS

Cooling
Relaxing

INDICATIONS

Functional nervous exhaustion
Post-febrile nervous weakness
Chorea
Hysteria
Agitation
Epileptiform convulsions
Insomnia
Nightmares
Restless sleep
Delirium tremens
Nervous excitability

SAFETY

Reports of hepatotoxicity attributed to skullcap were later determined to be related to adulteration with germander.

Skullcap can potentiate the effects of sedative medications.

PREPARATIONS

Tincture
Infusion

ORIGIN

Northern areas of the Northern Hemisphere including Europe, Asia, and almost all of Canada and North America

GROWTH

Hardy perennial

FOUND IN

Marshes, fens, riverbanks, pond margins, and canalsides.

FOLK HISTORY

The Cherokee and other tribes used skullcap as a ceremonial plant to introduce girls to womanhood. It was also used to treat breast pain, promote menstruation, and help expel the placenta during childbirth. The Iroquois used an infusion of the root to treat smallpox and keep the throat clear.

European settlers and folk herbalists learned how to use skullcap from Native Americans. In the 19th century, herbal physicians brought it to Great Britain, where it was used to treat conditions such as anxiety, phobias, and seizures.

In the 19th century, Physiomedicalists used skullcap as a nerve tonic for conditions such as hysteria, epilepsy convulsions, and schizophrenia. They believed it had a deeper effect on the nervous system than other herbs.

The name skullcap
comes from the flower's resemblance to the helmets worn by European soldiers.

SCIENTIFIC RESEARCH/STUDIES

American skullcap (Scutellaria lateriflora): a randomised, double-blind placebo-controlled crossover study of its effects on mood in healthy volunteers

The use of Scutellaria lateriflora: a pilot survey amongst herbal medicine practitioners

Phytochemical and biological analysis of skullcap (Scutellaria lateriflora L.): a medicinal plant with anxiolytic properties

GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence

Anxiety disorders and GABA neurotransmission: a disturbance of modulation